San Carlos Island Vacations from $437

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $2,000 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

The Latest San Carlos Island vacation packages

Price found within the past 48 hours. Click for updated prices.
Stay Inn & Suites
LaPlaya Beach & Golf Resort - A Noble House Resort
The Perry Hotel Naples
Casa Ybel Resort
Inn on Fifth
Don't see what you're looking for?
See all available trips from Columbus to San Carlos Island
View all trips

Stay near popular San Carlos Island attractions

What to do in San Carlos Island

San Carlos Island Hotel Deals

Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers

4 out of 5
251 Crescent Street Fort Myers Beach FL
$265 nightly
The price is $296 total per night from Jul 1 to Jul 2
$296 total
Jul 1 - Jul 2
Total with taxes and fees
9/10 Wonderful! (2,278 reviews)
"I had a great stay at Margaritaville! The resort has a fun, relaxing beach vibe, and the rooms are beautiful and very comfortable with a true vacation feel. The beach was very nice and just steps away. We also really enjoyed the pool area with a DJ playing music and a lively atmosphere. The drinks ..."

Reviewed on Jun 30, 2026

Margaritaville Beach Resort Fort Myers
Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

3.5 out of 5
1400 Estero Blvd Fort Myers Beach FL
Fully refundableReserve now, pay when you stay
$153 nightly
The price is $171 total per night from Jul 1 to Jul 2
$171 total
Jul 1 - Jul 2
Total with taxes and fees
9/10 Wonderful! (1,680 reviews)
"You have to pay for all the amenities (parking, beach chairs and umbrella at the beach … Very low pressure for showering. The music very loud from 9 am to 10 pm , very nice balcony with ocean view but impossible to relax… I’ll not recommend for relaxing time."

Reviewed on Jun 30, 2026

Lani Kai Beachfront Resort
Sanibel Island Beach Resort

Sanibel Island Beach Resort

3 out of 5
1231 Middle Gulf Dr Sanibel FL
Fully refundableReserve now, pay when you stay
$254 nightly
The price is $280 total per night from Jul 1 to Jul 2
$280 total
Jul 1 - Jul 2
Total with taxes and fees
9.2/10 Wonderful! (2,069 reviews)
"The property is great, from the rooms to the beach it was a great stay"

Reviewed on Jun 29, 2026

Sanibel Island Beach Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best San Carlos Island Vacation Packages

San Carlos Island Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Southwest Florida Intl. Airport (RSW)

More vacations you might like

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.